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Bodybuilders often take HGH in exogenous form to increase HGH production, increasing muscle mass and fat loss. Since no human (or animal) evidence exists for the effects of exogenous HGH on muscle growth or loss, Examine has only used data for research publications in which a human participant took exogenous HGH and compared him/her to a group of people who took insulin-like growth factor-1 or placebo (see for examples) in order to show a potential impact of exogenous HGH on muscle growth; therefore, there is no actual scientific study in humans showing a benefit. As noted in the previous section, we do know that HGH has been found to increase muscle mass in individuals that are currently or formerly on a HGH-only supplement regimen; however, this has been mostly in individuals with hypoplastic pituitary glands; as noted above, this is usually achieved by means of HGH antagonists which are approved for human use. Because many persons are using exogenous HGH on a regular basis not to gain muscle mass, but in an attempt to improve muscle mass through hypertrophy, we do not currently have a lot of data about whether this occurs for the HGH group versus those that are currently taking the drug. Since the exact mechanisms responsible for the effects of exogenous HGH are still unclear, it is difficult to recommend exogenous HGH as a supplement and/or bodybuilding intervention. A bodybuilding drug or supplement intervention does not appear to be the best way to increase your muscle mass. Exogenous HGH is not advisable for use as a muscle-building drug or supplement for the following reasons: It is not approved for human use. Exogenous HGH has an entirely different effect than exogenous insulin-like growth factor-1 or the hormone GH, and may result in unwanted side effects, and is likely to be less effective than other ways to achieve muscle mass. Exogenous HGH may not be beneficial for athletes (unless you use it on an individual basis). Insulin-like growth factor-1 also has an additive effect on protein metabolism and may also be useful for endurance-trained individuals; therefore, the added benefits to bodybuilding athletes in relation to HGH should not be considered as a direct reason to use or use for bodybuilders. As is mentioned earlier, the study design of Examine does not match the methods of assessing protein metabolism that are recommended for any medical professional. In addition, Examine only reported the benefits of Exogenous HGH in relation to body composition when taking an intercalary dose of exogenous HGH. Therefore, the Related Article: